1 Global Nicotinamide Mononucleotide (NMN) Market Size (Value) and CAGR (2024-2033)
In 2024, the global Nicotinamide Mononucleotide (NMN) market was valued at USD 416.61 million, with a CAGR of 28.5% from 2024 to 2033.
Nicotinamide mononucleotide is a nucleotide derived from ribose and nicotinamide. Ribonucleotide is the basic structural unit of nucleic acid RNA. It consists of a nicotinamide group, a ribose sugar, and a phosphate group. is a natural molecule present in all species. Nicotinamide mononucleotide (NMN) is one of the major precursors of nicotinamide adenine dinucleotide (NAD +), an essential enzyme for a variety of key cellular functions, including metabolism, DNA repair, cell growth, and survival.
Figure Global Nicotinamide Mononucleotide (NMN) Market Size (M USD) and CAGR 2024-2033
2 Nicotinamide Mononucleotide (NMN) Market Drivers
The global market for Nicotinamide Mononucleotide (NMN) has experienced significant growth in recent years, driven by a variety of factors. One of the primary drivers is the increasing demand from key regions, particularly Asia Pacific, which accounted for over 50% of the global market share in 2022. This region’s large population, aging demographics, and rising disposable incomes have fueled the demand for NMN products. For instance, China’s aging population and growing awareness of health and wellness have led to a surge in NMN consumption. The country’s cross-border e-commerce platforms have also facilitated the import of NMN products, making them more accessible to consumers.
Another significant driver is the growing demand from key applications, particularly in the health care and cosmetics sectors. NMN’s ability to boost NAD+ levels, which are crucial for cellular health and anti-aging effects, has made it a popular ingredient in dietary supplements and cosmetic products. Companies such as GeneHarbor, Herbalmax, and Shinkowa Pharmaceutical have developed high-quality NMN products that cater to this demand. Additionally, the inclusion of NMN in food raw materials lists in countries like Japan and the United States has opened up new opportunities for its application in the food industry.
3 Nicotinamide Mononucleotide (NMN) Market Restraints
Despite its promising growth prospects, the Nicotinamide Mononucleotide (NMN) market faces several challenges and restraints. One of the primary challenges is the presence of counterfeit and inferior products in the market. The increasing popularity of NMN has attracted many small manufacturers and retailers, leading to a proliferation of substandard products. These counterfeit products not only affect the reputation of NMN but also pose potential health risks to consumers. For example, some unscrupulous traders may use nicotinamide instead of NMN, causing adverse effects such as skin flushing, nausea, and dizziness.
Another significant challenge is the regulatory uncertainty surrounding the use of NMN in food and supplements. While NMN has been approved as a food raw material in Japan and as a dietary supplement in the United States, it cannot be claimed to have therapeutic or preventive effects on diseases. This regulatory ambiguity may limit the market’s potential for expansion.
4 Global Nicotinamide Mononucleotide (NMN) Market Size by Type in 2024
In 2024, the global NMN market is projected to consume a total of 53,508 kilograms. The market is predominantly driven by the demand for high-purity NMN, with the Content Above 98% category accounting for the majority of the consumption. Specifically, the Content Above 98% type is expected to consume 47,947 kilograms, representing approximately 89.61% of the total market. This high-purity NMN is highly sought after due to its superior quality and effectiveness in various applications, particularly in health care products and cosmetics. High-purity NMN ensures that the product contains a significant amount of the active ingredient, leading to more effective results in terms of boosting NAD+ levels and providing anti-aging benefits.
The Content Below 98% type is expected to consume 5,561 kilograms, accounting for about 10.39% of the total market. This type of NMN, with a lower purity level, is often used in applications where high purity is not a critical requirement. It is suitable for general health care products and some cosmetic formulations where cost-effectiveness is a significant factor. The lower purity level may also be advantageous for bulk production and applications where the end product does not require the stringent quality standards of high-purity NMN.
Table Global Nicotinamide Mononucleotide (NMN) Market Consumption (Kilogram) by Type in 2024
Type | Market Consumption (Kilogram) 2024 | Market Share 2024 |
Content Below 98% | 5561 | 10.39% |
Content Above 98% | 47947 | 89.61% |
5 Global Nicotinamide Mononucleotide (NMN) Market Size by Application in 2024
In the health care products segment, NMN is highly valued for its role in boosting NAD+ levels, which are crucial for cellular health, metabolism, and anti-aging effects. This segment is expected to consume 43,898 kilograms of NMN in 2024, accounting for approximately 82.04% of the total market. The demand for NMN in health care products is driven by the growing awareness of health and wellness among consumers, as well as the increasing demand for dietary supplements and nutraceuticals that promote healthy aging and improve overall health.
The cosmetics segment is another significant application area for NMN, leveraging its anti-aging properties to develop products such as creams, serums, and masks. In 2024, this segment is projected to consume 6,095 kilograms of NMN, representing about 11.39% of the total market. The demand for NMN in cosmetics is driven by the increasing consumer interest in anti-aging and skin health products, as well as the growing trend of incorporating natural and scientifically-backed ingredients into cosmetic formulations.
Table Global Nicotinamide Mononucleotide (NMN) Market Consumption (Kilogram) by Application in 2024
Application | Market Consumption (Kilogram) 2024 | Market Share 2024 |
Health Care Products | 43898 | 82.04% |
Cosmetics | 6095 | 11.39% |
Others | 3515 | 6.57% |
6 Global Nicotinamide Mononucleotide (NMN) Market Size by Region in 2024
The Asia Pacific region is the largest market for NMN, with a projected value of 222.91 million U.S. dollars in 2024. This region’s dominance is driven by its large population, aging demographics, and increasing disposable incomes, particularly in countries like China and Japan. The growing health consciousness and demand for high-quality health care products and cosmetics in this region have fueled the NMN market’s expansion.
The Americas, with a projected market value of 93.08 million U.S. dollars in 2024, is the second-largest market for NMN. The United States is a key driver in this region, with a strong demand for health care products and dietary supplements. The growing awareness of health and wellness, combined with the increasing adoption of NMN-based products, has contributed to the market’s growth.
Europe is another significant market for NMN, with a projected value of 92.29 million U.S. dollars in 2024. The region’s market growth is driven by the increasing demand for health care products and cosmetics, as well as the growing interest in natural and scientifically-backed ingredients. The regulatory environment in Europe, which supports the development and approval of new health care products, has also contributed to the market’s expansion.
Figure Global Nicotinamide Mononucleotide (NMN) Market Size by Region in 2024
7 Major Players in Global Nicotinamide Mononucleotide (NMN) Market
7.1 GeneHarbor
GeneHarbor is a leading company in the NMN market, known for its pioneering work in the production of high-purity NMN. Established in 2004, GeneHarbor operates primarily out of China and has a global sales presence. The company specializes in the production of active pharmaceutical ingredients and intermediates using an enzymatic approach. GeneHarbor’s proprietary platform technology aims to reduce the cost and increase the lifespan of enzymes, which is crucial for the production of NMN.
Their NMN product, NMN 12000, is designed to significantly increase NAD+ levels in the body, promoting healthy aging and supporting various physiological functions. In the most recent year, GeneHarbor reported a revenue of 98.20 million U.S. dollars, with a gross margin of 49.69%.
7.2 Herbalmax
Herbalmax, founded in 1999, is another major player in the NMN market, focusing on the development, manufacturing, and licensing of scientifically sound and clinically approved natural dietary supplements. The company is headquartered in North America and has a global sales reach. Herbalmax’s NMN product, Reinvigorator, is an advanced daily supplement that boosts cellular repair, optimizes metabolism, and increases energy.
The product is formulated with a proprietary blend of ingredients, including β-Nicotinamide Mononucleotide, Acai Berry extracts, Rhodiola Rosea, Notoginseng, and Epimedium. In the most recent year, Herbalmax reported a revenue of 45.04 million U.S. dollars, with a gross margin of 52.63%.
7.3 Shinkowa Pharmaceutical
Shinkowa Pharmaceutical, established in 2016, is a biotechnology company based in Japan. The company is known for its rigorous development of productive aging science and its commitment to improving the well-being of customers and society. Shinkowa Pharmaceutical’s NMN product, Mirai Lab’s NMN Supplements, is part of the “NMN Pure” series, which contains rare NMN ingredients with over 99% purity.
The company’s NMN Pure 900 Plus is a high-purity NMN supplement that supports healthy aging and NAD+ production. Shinkowa Pharmaceutical reported a revenue of 10.80 million U.S. dollars in the most recent year, with a gross margin of 46.76%. This reflects their growing presence in the NMN market and their focus on delivering high-quality, high-purity NMN products.